Selected Publications

1. Herpes simplex virus type 1/adeno-associated virus hybrid vectors. de Oliveira AP, Fraefel C.

Open Virol J. 2010 Jun 18;4:109-22. doi: 10.2174/1874357901004030109.

2. Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector. Cortés ML, Oehmig A, Saydam O, Sanford JD, Perry KF, Fraefel C, Breakefield XO. Mol Ther. 2008 Jan;16(1):81-8.

3. Integration of active human beta-galactosidase gene (100 kb) into genome using HSV/AAV amplicon vector. Oehmig A, Cortés ML, Perry KF, Sena-Esteves M, Fraefel C, Breakefield XO. Gene Ther. 2007 Jul;14(14):1078-91.

4. Chimeric herpes simplex virus/adeno-associated virus amplicon vectors. Glauser DL, Ackermann M, Saydam O, Fraefel C. Curr Gene Ther. 2006 Jun;6(3):315-24. Review.

5. Herpes simplex virus type 1 amplicons and their hybrid virus partners, EBV, AAV, and retrovirus.

Oehmig A, Fraefel C, Breakefield XO, Ackermann M. Curr Gene Ther. 2004 Dec;4(4):385-408. Review.

6. Herpes simplex virus type 1/adeno-associated virus hybrid vectors mediate site-specific integration at the adeno-associated virus preintegration site, AAVS1, on human chromosome 19.

Heister T, Heid I, Ackermann M, Fraefel C. J Virol. 2002 Jul;76(14):7163-73.

7. HSV/AAV hybrid amplicon vectors extend transgene expression in human glioma cells. Johnston KM, Jacoby D, Pechan PA, Fraefel C, Borghesani P, Schuback D, Dunn RJ, Smith FI, Breakefield XO. Hum Gene Ther. 1997 Feb 10;8(3):359-70.